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ALIAS™
Autosampler

ALIAS™ is a generic autosampler for HPLC and LC-MS using state-of-the-art injection technology with fast injection and wash cycles. Effcient, multi-solvent needle wash virtually eliminates carry-over. ALIAS™ handles well plates and sample vials, either open or sealed, and provides true 4°C sample cooling. Its compact, stackable design and unrivalled performance make the ALIAS™ autosampler the best ft for your HPLC system… and your UHPLC system!

Features

Alias
Autosampler

  • Metal free sampling with silicacoated steel needle and PEEK valve (option)
  • Reagent addition and mix capabilities for derivatization, dilution, internal standard addition
  • Optional 6-port solvent selection valve for extended selection of reagents for needle wash and reagent addition (option)
  • Solvent Selection Valve (SSV)
  • Integrated Stream Switching (ISS). Optional extra high pressure 6-port switching valve for column switching or other stream switching applications up to 18,000 PSI
  • Quick-ft injection valve for fast service

Specifications

  • Injection modes: Full-loop、Partial loop-fll、µL-pick-up（Pressure Assisted Sample Aspiration using ~10 PSI sample headspace pressure to avoid air bubbles in sample lines.）
  • Injection volume: Programmable from 0 µl – 9999 µL 1 µL increments（Max injection volume depends on installed sample loop and injection mode）
  • Injection precision: Full-loop injection ‹ 0.3% RSD Partial loop-fill ‹ 0.5% RSD µL -pick-up ‹ 1.0% RSD For injection volumes › 5 µL
  • Sample viscosity: 0.1 – 5 cP
  • Injections per vial/well: Max 9
  • Syringe volume: 500 µL standard , 250, 1000 and 2500 µL optional
  • Needle wash (Inside and outside needle wash with drying. Wash can be programmed between injections and between vials/wells): 1 solvent 5 additional wash solvents Programmable volume from a 250 µL wash reservoir SSV option required
  • Injection cycle time: ‹ 60 seconds [‹ 20 seconds, with typical 10 ul injection (loop fill with rinse buffer)]
  • Valve switching time: 60 msec
  • Wetted parts: SS316, PTFE, TEFZEL, VESPEL, glass, For Bio-kit option: PEEK and Coated-steel (needle) instead of SS316
  • Carry-over: ‹ 0.05% with standard wash Typically ‹ 0.01% with extra wash ( “zero carry-over” can be accom- plished with ALIAS™ wash capabilities)
  • Sample capacity: Microtiter plates: 2; Vials: 2x 48 (1.5 mL) or 2x 12 (10 mL) - optional (Microtiter plates according to SBS standards. 96-well high and low and 384-well).
  • Maximum vial/MTP height: 47 mm including cap
  • Sample cooling: Minimum: 4°C ± 2°C Maximum: ambient temp -3°C (Measured as air temperature in sample compartment for maximum ambient temperature 25°C and maximum humidity 80%)
  • Dimensions： 300 x 510 x 360 mm (wxdxh) 300 x 575 x 360 mm for ALIAS™ cool
  • Weight: 19 kg ；21 kg for ALIAS™ cool
  • Max load on top cover：65 kg
  • Power requirements: 95 - 240 Volt AC ± 10%; 50-60 Hz; 200 VA
  • Sound pressure level: LeAq ‹ 70 dB
  • Working temperature: 10 – 40 °C Indoor use only
  • Humidity: 20 – 80% RH
  • Outputs: Single auxiliary output which can be programmed as inject marker (default), alarm, etc Contact closure Vmax = 28 Vdc/Vac, Imax = 0.25A
  • Inputs: 2 programmable TTL inputs. (Free programmable as next injection (default), freeze or stop command)
  • PC interface: RS 232 is standard. Extra serial RS232 for Multilink functionality allows upgrading for Symbiosis Pico
  • Software: SparkLink 4.0 (included); Driver for Analyst (Analyst is a registered trademark from Applied Biosystems) 1.4.1 and up; ALIAS™ Service Manager
  • Door-open sensor: Needle movement speed reduction if door is open
  • Missing vial/well plate sensor: User programmable response to missing vial: skip vial or stop run
  • Software malfunction:“Watchdog” function in FPGA for embedded software control
  • Safety: CE; CSA (UL), ROHS
  • Installation category: II (according to IEC-1010)
  • Pollution degree: 2
  • Quality: ISO 9001 certified

Applications

Clinical pharmacokinetics, proteomics, environmental monitoring, food safety